Multiplex Phenotype and Function from Less Sample in Record Time Intellicyt® iQue Screener PLUS

Speed to actionable results from every well

The Intellicyt iQue Screener PLUS platform is an integrated instrument, software, and reagent system that enables rapid, high-content, multiplexed analysis of cells and beads in suspension. The iQue Screener PLUS platform is ideal for scientists who need data from suspension-cell assays fast. While standard flow cytometry is commonly used for analysis of cells and beads in suspension, it offers limited capabilities in screening applications for assay throughput, automation, sample/reagent volume requirements, and ease of use. With its high-throughput flow cytometry-based foundation, the Intellicyt advantage includes:

Speed

Relieve capacity bottlenecks with the fastest plate sampling, integrated analysis, multiplexed no-wash assays, and novel data reduction tools.

Miniaturization

Conserve precious samples and reagents by sampling as little as a single microliter from miniaturized assay volumes.

Content

Perform high content, multiplexed analysis of cells, beads and secreted proteins in suspension.

Usability

Enjoy a simple, scalable, multi-user environment with walkaway automation, comprehensive analysis and visualization tools, and other features not found in traditional solutions.

Insight

Dramatically reduce time to decision with novel visualizations that facilitate the fastest path to actionable results, even from complex data sets.

Multiple Configurations Based on Your Need

The Intellicyt iQue Screener PLUS comes in multiple optical configurations and flexible plate formats

ConfigurationBlue-RedViolet-Blue-RedViolet-Yellow-Blue
Lasers488nm, 640nm405nm, 488nm, 640nm405nm, 561nm, 488nm
Detection Channels81515
Plate Types96- and 384-well, 384- and 1536-well (Blue-Red HD)96- and 384-well96- and 384-well
Min Sampling Time< 5 minutes/96 wells, < 20 minutes/384 wells
Min Sample Aspiration1 µL
Detection RateUp to 35,000 events/second
Dynamic Range> 7 Decades

Download Specification Sheet

Antibody Discovery & Development

Increase data throughput and quality by multiplexing antibody binding, function, and titer across the process.

  • Antibody screening
  • Functional Profiling
  • Cell line development

Adoptive Cell Therapy or Immuno-oncology

Assess multiple cell parameters faster, with fewer cells and less reagents.

  • Immune cell killing
  • Immune cell assessment
  • Cytokine profiling

Small Molecule Discovery

Perform high-content phenotypic screening of immune biology across the drug discovery process.

  • Primary immune cell screening
  • Yeast and bacterial assays
  • Target identification with siRNA and CRISPR

The iQue Screener allows us to run high throughput screening assays against primary cell types monitoring drug action in a way that simply wasn't possible.

Steve Rees, Vice President, Discovery Biology, AstraZeneca

In-solution, cell-based assays are the way forward and the ability to do so with the iQue Screener in a 384-well high-throughput format has been extremely useful to us. We can now use one third of the materials and screen 4 times more antibody clones in the same amount of time, obtaining more compelling data for ourselves and our clients.

Andrea Gorlani, PhD, Scientist ModiQuest Research

Matt Johnson

The iQue Screener will scale our project throughput in a way that would have been impossible using our current methods.

Matt Johnson, PhD, CTO Avacta Life Sciences

Sofie Pattjin

In short, the iQue offers flow cytometry capabilities at real high throughput, making it the perfect instrument for cell and bead based screenings.

Sofie Pattijn, CTO ImmunXperts

Features

The Intellicyt iQue Screener PLUS Accelerates Your Research

Instrumentation Features 1

Rapid, Walkaway Plate Processing

  • Patented, rapid microvolume sampling processes 96 well plates in as few as 5 minutes or 384 well plates in 20 minutes.
  • Samples are delivered to detectors in an air-gap delimited stream, so an entire plate of data can be processed at one time.
  • Generous cartridge station allows for unattended multiple plate processing.
  • Interface and integration development kit allows easy use of your favorite automation.
  • Assay protocols are configurable for any point during or after plate sampling.
  • Perform routine tasks with the touch of a button, including system cleaning, plate map calibration, shutdown, and even fluidics refilling (with the QMax Refill Module).

Instrumentation Features 2

Real-time Data Acquisition and Analysis and Dynamic Visualization of Results

Rapid assay optimization – adjust a gate to see updated plate-wide analysis in real time.

  • Easy, interactive assay development and decision environment that is reproducible across plates.
  • Plate level annotation, analysis, and visualization integrated within the standard population selection tools.

Ordering Information

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Product Description

Intellicyt iQue Screener PLUS Platform

Includes Intellicyt iQue Screener PLUS, computer workstation with Forecyt Software (one license) Request a Quote or Demo

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