Bioprocessing
Identifying and selecting optimal clones that secrete high levels of antibody into the culture supernatant is critical to the cell line development process. Current methods identify optimal antibody producers by measuring IgG concentration. The iQue® Human IgG Titer and Viability kit, rapidly correlates IgG quantitation along with cell health and growth readouts in a single, cost-effective assay.
Complete IgG quantitation (per cell and total IgG produced) in addition to cell density information provides a more accurate picture as to which clones are optimal producers.
Bioprocessing for Antibody Discovery Resources
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Improving Bioprocessing Efficiency and Quality without Compromising Safety or Cost
To accelerate the commercialization of biotherapeutics, it is essential for organizations to optimize their processes by integrating advanced analytical tools that maximize quality, safety, and efficacy.
The Octet® BLI platform is a prime example, as it enables real-time, label-free analysis for a variety of applications, including titer analysis, residue analysis, glycosylation profiling, potency assay development, Fab activity assay development, and more. Simplify bioprocessing workflows and achieve greater efficiency, while maintaining high standards of quality, safety, and efficacy.
Label-Free Assays for Regulated Process Development and Quality Control (QC)
The Octet® BLI platform simplifies the development of methods for in-process and lot release testing, which can be easily transferred to QC. User-friendliness and high-throughput capacity are prerequisites, which can enhance productivity by up to 40 times compared to conventional enzyme-linked immunosorbent assay (ELISA).
