Cell-based receptor-trafficking assays using the iQue Screener platform

Speaker

Dr. Jonathan Jarvik, PhD

Institution

SpectraGenetics

Description

G-protein-coupled receptors (GPCRs), the largest family of cell surface receptors that respond to variety of external signals, are an important class of proteins that serve as targets for therapeutic development. Trafficking of GPCRs and other receptors from the plasma membrane to the cell interior and back are standard features of most signal transduction pathways.

This webinar will review how researchers at SpectraGenetics were able to run a new family of cell based assays to detect and quantify GPCR trafficking events using the iQue Screener platform.

Learn more about:

• A novel GPCR internalization and trafficking assay developed by SpectraGenetics
• How the high throughput capability of iQue Screener platform provided the opportunity to screen a large number of compounds for their effect on GPCRs.