Attend the talk to be delivered by Mike Dyson, Chief Technology Officer at IONTAS Ltd that will highlight how the Intellicyt® iQue Screener platform was used in their antibody screening workflow.
Mammalian display: antibody discovery, affinity maturation and developability screening in IgG format
Speaker: Mike Dyson, Chief Technology Officer, IONTAS Ltd.
Date and Time: Thursday, October 29, 5:50 pm
- Integration of IgG libraries into mammalian cells by CRISPR/Cas9 and TALE nucleases
- Multi-parametric FACS used to discover antibodies with desired specificity, binding affinity, species cross-reactivity and expression level
- Mammalian display for ultra-high throughput developability screening
- Utility of Intellicyt iQue for human antibody screening