Visit IntelliCyt at SLAS2016, the leading annual screening and automation meeting, in San Diego, CA. We will be at Booth #941. See the details of our program below.
Monday, January 25th
12:30pm – 1:45pm -Room 11A | Exhibitor Tutorial
Tutorial Title: Nimble Meets Quick: True Immunology Screening with the only True High Throughput Flow Platform
IntelliCyt offers the only integrated solution that enables screening of cells and secreted proteins in suspension to for maximum insight – at the speed of light. Our bench top platform the iQue Screener is an integrated instrument, software, and reagent system that optimizes assay workflow from sample preparation through results by delivering the fastest time to results using the lowest volume assays to provide rich and insightful data in minutes.
Learn more from three industry experts as they talk about how the iQue Screener accelerated their research and provided better insight into complex biology.
|Now, witness the power of this fully operational battle station.
Dr. Mark Wigglesworth, Director High Throughput Screening, AstraZeneca, United Kingdom
|This presentation will describe the generation and application of a dual iQue screening platform to deliver a screen in excess of 500K wells, as well as overview the learning’s from this experience and other screening applications. Dr. Wigglesworth will talk about AstraZeneca’s future plans with the iQue Screener platform and how they envisage being able to use this for extended high throughput screening activities throughout 2016.
|An Automated HT Flow Cytometry Platform Enabling Measurement of Immune Signaling in Whole Blood for Lead Evaluation
Dr. Mark P. Fereshteh, Research Investigation, Immuno-Oncology based Lead Discovery, Bristol-Myers Squibb, USA
|This talk will highlight the need for a whole blood based immune signaling assay and the challenges of developing such an assay. It will describe how the rapid microvolume sampling and automation compatibility of the iQue Screener platform enabled routine screening of ~2000 whole blood samples per day. Finally, the analysis of high content data in ForeCyt Software will be discussed.
|High-Throughput Screening of Monoclonal Antibodies to Multiplexed Antigens
Dr. Benjamin Hoffstrom, Director of Antibody Technology, Fred Hutchinson Cancer Research Center, USA
|The Fred Hutchinson Antibody Technology core lab offers time and cost-efficient custom monoclonal antibody development for in-house and external clients. Since its inception in 1995, the lab has developed over 7500 hybridoma cell lines from mice, rats, and rabbits, several of which are commercially licensed reagents. This talk will highlight the ability of the iQue Screener platform to simultaneously screen for monoclonal antibodies to 5 different antigens. The platform uses a two-stage workflow coupling a combination of target-based hybridoma colony selection and cytometric bead-based target deconvolution. The target identification assay is 25-50 times more sensitive than traditional ELISA-based screens, which allows for rapid ranking of several thousand antibodies based on target affinity and murine isotype. A general overview of the workflow will be outlined and specific projects will be highlighted.
|Phenomenal spectral bandwidth….minute assay volumes! Introducing iQue Screener PLUS
Joseph Zock, Senior Director, Product Management, IntelliCyt Corporation, USA
|The recently released iQue Screener PLUS provides the spectral power of 13 simultaneous colors using 3 laser (405 nm, 488 nm, 640 nm) excitation while retaining the industry leading plate processing speed, micro volume sampling and plate level analytics the iQue Screener family is known for. The iQue Screener PLUS, once again, expands the envelope of true immunology screening by combining immunophenotyping, cell health, cell function, and cytokine profiling into single high content assays for immuno-oncology, immune targets, and immuno-therapy applications.
Tuesday, January 26th
1:00pm – 3:00pm | Poster # 2030:
Profiling of a Compound Library Biased Toward Immunomodulating Agents: High-Throughput Screening of Immunophenotype, Viability, Proliferation, and Cytokine Secretion on a Single Platform
1:00pm – 3:00pm | Poster #3004
iQue Screener PLUS: A High Throughput Screening System for Profiling Multiplexed Cellular and Secreted Immunological Markers
See you there!